| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 가을 (10/26 ~ 10/28, 제주국제컨벤션센터(ICCJEJU)) |
| 권호 |
20권 2호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Poly(L-lactide) nanocomposites with surface-modified magnesium hydroxide for enhancement of mechanical and biological properties |
| 초록 |
Poly(L-lactide) (PLLA) is one of biodegradable polymers and is widely used in medical applications. When once PLLA is implanted into the body, however, the inflammation occurs that is attributed to the formation of acidic by-products during its degradation. In addition, the poor interfacial interaction between MH and PLLA leads to decrease the mechanical properties of PLLA nanocomposites. In this study, we prepared the PLLA nanocomposite with surface-modified MH via a melt extrusion process to enhance their interfacial compatibility. The effects of surface modification on interfacial compatibility were investigated by TGA, UTM, and SEM. In vitro cell viability and inflammation response were also evaluated. The results showed that surface modification of MH could effectively improve mechanical modulus and reduce the inflammatory response of the PLLA nanocomposites. |
| 저자 |
강은영1, 박광숙1, 이유진1, 강종희1, 김익환2, 정윤기1, 한동근1
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| 소속 |
1한국과학기술(연), 2고려대 |
| 키워드 |
coronary stent; PLLA; magnesium hydroxide; cytotoxicity
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| E-Mail |
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