| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
An In vivo Study for bone regeneration using Small Intestine Submucosa sponge with rat Bone Marrow Stem Cells. |
| 초록 |
Bone tissue engineering seeks to develop strategies to repair and regenerate bone at sites of bone defects and damage caused by trauma or disease without the limitations and drawbacks of current clinical autografting and allografting treatments. The ideal scaffold should possess an environment capable of supporting growing bone tissue and demonstrate good biocompatibility. SIS is a biomaterial that can be easily produced for use as an experimental scaffold for tissue engineering applications. We describe the no previous study has examined SIS sponges as an in vivo bone-regenerative scaffold for rBMSCs, which are the most commonly used seed cells for bone tissue engineering. And we applied three dimensional SIS sponges as a scaffold using an experimental rat cranial bone-defect model, investigating whether the implantation of an SIS sponge could conduct newly forming bone across full thickness. In addition, we evaluated tissue-engineered bone formation using micro-CT and histology. |
| 저자 |
강윤미, 김이슬, 김경해, 강꽃님, 박고운, 김재호, 민병현, 이해방, 김문석
|
| 소속 |
아주대 |
| 키워드 |
SIS; bone defect; scaffold
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| E-Mail |
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