| 초록 |
Enantiomers are classified as a group of molecules with chiral centers with non-superimposable mirror images. The separation of the racemic mixtures is a highly critical task in pharmaceutical or in the food industry, since many of the enantiomer pairs will have significantly different responses regarding to the different chiral configurations. Metal organic frameworks (MOFs) have been dignified as a high performance material in the field of separations due to the large surface area for adsorption, wide range of creative pore size, and diversity in structuring tunable for each applications. Zeolite imidazole frameworks are a class of MOFs, where the cage is consisted of imidazole group ligand attached to zinc metal ions, that are relatively cheap in production cost, easy to synthesize and extremely stable in water. Herein, we demonstrate enhanced enantiomer separation performances of the ZIF-8 derivatives, histidine-ZIF8 (HIS-ZIF) histidine-methyl-ester-ZIF8 (HME-ZIF), and further show the effect of ion-exchanging the acid moiety of the histidine cage to show sterical and interactive effect of the chiral resolution centers. |
