학회 | 한국화학공학회 |
학술대회 | 2022년 봄 (04/20 ~ 04/23, 제주국제컨벤션센터) |
권호 | 28권 1호, p.1264 |
발표분야 | [주제 12] 화학공학일반(부문위원회 발표) |
제목 | Synthesis and characterization of gold nanoparticle-doped and Quercetin loaded liposomes using L-α-phosphatidylcholine for effective drug delivery system |
초록 | Diffusivity, pH and solubility are important in the field of drug delivery systems (DDS) for biomedical applications. In particular, because active drug molecules are amphiphilic, such physicochemical parameters play a very important role in moving drug molecules to specific sites. Among the drug delivery systems (DDS), liposome drug carriers perform better than conventional toxic nanoparticle drug carriers for theranostic applications. AuNP is also considered the most interesting nanomaterial because of its unique optical-electrical properties. AuNPs have potential applications for medical imaging, drug delivery, tumor diagnosis and treatment This study focused on the characterization of AuNP, Lip-Quercetin, and Lip-Quercetin@AuNP. AuNPs was charaterized via UV-vis, TEM, and FT-IR to ensure that AuNPs were synthesized well. L-α-Phosphatidylcholine was used to make a phospholipidic double layer, and Quercetin was added to hydrate to synthesize liposomes via evaporator. Lip-Quercetin and Lip-Quercetin@AuNPs were charaterized via UV-vis and SEM to confirm that the particles synthesized well. |
저자 | 이지영, 김종성 |
소속 | 가천대 |
키워드 | 생물화공(Biochemical Engineering) |
원문파일 | 초록 보기 |