초록 |
Riboregulatory genetic control has been attracting increasing attention as recent research reveals that noncoding RNA elements and ligand-binding regulatory mRNAs play pivotal roles in control over celluar gene expression through several mechanisms including RNA interference and riboswitching. We are interested in constructing synthetic biological circuits by exploiting the riboregulatory elements, because it promises great potential to biomedical applications and research tools for simplifying biological systems into reconstitutive modules. Here we present a novel synthetic riboregulatory system that is switchable by small chemicals. |