화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2012년 봄 (04/25 ~ 04/27, 제주 ICC)
권호 18권 1호, p.773
발표분야 열역학
제목 Thermodynamic Properties of Aqueous Two-Protein Solutions
초록 The generalized Lennard-Jones (GLJ) pair potential function is employed to represent the osmotic properties of globular two-protein systems. The equation of state developed in this work is based on a hard-sphere reference with perturbations introduced through a potential function to account for electrostatic forces and for attraction between protein particles. To describe osmotic properties of protein systems, energy parameter is fitted to experimental cloud point temperature data for corresponding protein/salt systems. Those parameters are then introduced to calculate phase behavior in the aqueous two-protein system. Agreement with experimental data is reasonable in the given pH and ionic strength range with no additional binary parameters.
저자 배성진1, 김인하2, 배영찬1
소속 1한양대, 2LG전선
키워드 Osmotic pressure; second virial coefficient; partition coefficient
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