| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Characterization and Fabrication of Duck Feet-derived Collagen and Polyvinyl Alcohol Scaffolds for Skin regeneration |
| 초록 |
The purpose of this study was to develop a wound dressing made from a duck feet derived collagen (DC) with enhanced healing effect. The hydrogel was prepared with poly(vinyl alcohol) (PVA) and DC. We performed compressive strength, SEM, swelling test and FT-IR for mechanical property and morphology of DC/PVA scaffold. For biocompatibility test, NIH/3T3 mouse fibroblasts were cultured in the DC/PVA scaffold for 3days. Cell proliferation and viability were measured via MTT assay. 10% DC/PVA scaffold showed a higher biocompatibility in vitro and the better ability of cell adhesion and growth, compared to PVA scaffolds. The in vivo assay also revealed the better results in 10% DC/PVA scaffolds and improved the wound healing process in rats. In conclusion, the 10% DC/PVA scaffold is a potential wound dressing with enhanced wound healing effect. This research was supported by the Brain Korea 21 PLUS Project, NRF and Technology Commercialization Support Program (KMIFAFF 814005-03-1-HD020). |
| 저자 |
신재훈1, 송정은1, 이동원1, 박찬흠2, 서동삼3, 강길선1
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| 소속 |
1전북대, 2한림대, 3세원셀론택 |
| 키워드 |
Wound healing; Duck Feet-derived Collagen; Poly(vinyl Alcohol) (PVA); Hydrogel
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| E-Mail |
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