| 학회 |
한국화학공학회 |
| 학술대회 |
2012년 봄 (04/25 ~ 04/27, 제주 ICC) |
| 권호 |
18권 1호, p.467 |
| 발표분야 |
생물화공 |
| 제목 |
Immobilization of Tyrosinase on Electroenzymatic Synthesis of L-DOPA |
| 초록 |
Parkinson's disease (PD) in humans is caused by dopamine deficiency in the nigro-striatum. Dopamine in dopamine neurons is synthesized from L-3,4-dihyroxy phenilalanine (L-DOPA). In this study, electroenzymatic synthesis of L-DOPA was investigated. Tyrosinase was immobilized on glassy carbon electrode and the reaction was conducted under the reduction potential of DOPAquinone. Variation of pH and temperature were investigated. The optimum condition of electroenzymatic immobilized tyrosinase for synthesis of L-DOPA was obtained. Immobilization of tyrosinase on electroenzymatic synthesis was found to be promising way for producing L-DOPA. |
| 저자 |
Siti Fauziyah Rahman1, 박돈희2, Siramulu Gobikhrisnan3, Natarianto Indrawan1, 박석환2, 박재희3, 선우창신1, 류화원2, 민경선3, 유영제1
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| 소속 |
1Interdisciplinary Program of Graduate School for Bioenergy and Biomaterials, 2School of Biological Science and Technology, 3Chonnam National Univ. |
| 키워드 |
L-dopa; Electroenzymatic synthesis; Immobilization Enzyme; Parkinson's disease
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| E-Mail |
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| 원문파일 |
초록 보기 |
