| 초록 |
Phospholipids are a major component of biomembrane , and research has recently been conducted in various fields for them. In this study, we investigate the physical properties of 1,2-dioleyl-sn-glycero-3-phosphocholine (DOPC) depending on the solvent characteristics. For MD simulation, we use AMBER Molecular Dynamics Packagae and lipid14 force field. The solvation model used in this study is the Implicit solvation model. Physical properties such as conformation and potential energy can be confirmed to vary depending on the properties of the solvent. The results of this study on single molecules could be used as the basis for the study of various types of phospholipid structures, including bilayers, micelles, and visicles. |
