| 학회 |
한국공업화학회 |
| 학술대회 |
2013년 가을 (10/30 ~ 11/01, 대전컨벤션센터) |
| 권호 |
17권 2호 |
| 발표분야 |
포스터-촉매 |
| 제목 |
One pot synthesis of indoles through tyrosine-meditated peptide-polypyrrole supported palladium catalyst |
| 초록 |
Since the indolic compounds have many biological activities and structural diversity, numerous synthetic approaches have been developed for the last decades. The well known approach to synthesize indolic compounds are cross-coupling reaction with transition metal catalysts. Moreover, one pot synthesis of indolic compounds has been the current issue in the field of pharmacology. However, direct synthesize indole ring system has been limited due to harsh reaction conditions. Recently, we have found that tyrosine containing peptide film can be used as a template for polymerizarion of pyrrol and fabrication Pd nanoparticles (NPs) on it. The tyrosine peptide-polypyrrole supported palladium catalysts (Tyr-peptide@PPy@Pd catalysts) afforded a good catalytic activity in one- pot synthesis of the indolic compounds from 2 haloanilinesin in water. |
| 저자 |
유재명1, 김영오1, 장형석1, 김요한1, 이상명2, 이윤식1
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| 소속 |
1서울대, 2강원대 |
| 키워드 |
peptide; self assembly; catalyst
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| E-Mail |
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