| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 가을 (10/20 ~ 10/22, 경주컨벤션센터) |
| 권호 |
46권 2호 |
| 발표분야 |
콜로이드 및 분자조립 부문위원회 Ⅰ,Ⅱ |
| 제목 |
Colloidal Supraballs of Mesoporous Silica Nanoparticles as Bioresorbable Adhesives for Hydrogels |
| 초록 |
Adsorption of polymers at the surface of mesoporous silica nanoparticles (MSN) has been shown to provide a versatile way to create adhesion between hydrogels or biological tissues. Nevertheless, above a critical number of deposited nanoparticles, multilayers accumulate at the interface and adhesion strength decreases as cracks easily propagate between weakly cohesive polymer-free nanoparticles. In order to suppress this limitation, we prepare spherical aggregates by spray-drying in which MSNs are strongly adhered by thermal annealing. Peeling tests show that the maximum adhesion energy reached with microscopic supraballs (SB-MSN) is significantly higher than the one achieved with non-aggregated non-porous or MSNs. It can be even further increased by using macroporous supraballs. Finally, SB-MSN degrade in biological media at the same rate as the elementary mesoporous nanoparticles, therefore offering an interesting combination of adhesion and bioresorbability for use as bioadhesives. |
| 저자 |
백재선1, 김상아1, 정대웅1, 방창현1, 방석호1, Laurent Corté2, 이기라3
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| 소속 |
1성균관대, 2PSL Univ., 3포항공과대 |
| 키워드 |
Adhesives; Hydrogels; Macroporous Supraballs; Mesoporous Silica; Spray Drying
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| E-Mail |
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