| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터) |
| 권호 |
15권 1호 |
| 발표분야 |
나노 |
| 제목 |
Mesoporous Silica Nanoparticles Decorated with Multiple Magnetite Nanocrystals for Simultaneous Enhanced MRI, Fluorescence Imaging and Drug Delivery |
| 초록 |
Fabrication of uniform mesoporous dye-doped silica nanoparticles immobilized with multiple magnetite nanocrystals on the surface (designated as Fe3O4-MSN) enabled simultaneous MRI, fluorescence imaging, and drug delivery. The integration of numerous magnetite nanocrystals on the silica surface resulted in synergistic magnetism that enhanced the MR signal. Small dye molecules incorporated in the silica framework imparted optical imaging modality. In addition, anticancer drug was able to be loaded into the pores of mesoporous silica nanoparticles for drug delivery. In vivo passive targeting of the nanocomposite particles to tumors was also demonstrated. |
| 저자 |
이지은, 이노현, 현택환
|
| 소속 |
서울대 |
| 키워드 |
mesoporous; drug delivery; MRI
|
| E-Mail |
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