| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
포스터-나노 |
| 제목 |
The Synthesis and Characterization of Novel Aggregation-induced Emission Nanoparticles Encapsulated with Biocompatible Polymers |
| 초록 |
Aggregation-induced emission (AIE) dyes have the property of increasing fluorescence at high concentrations, in contrast to the conventional dyes. AIE dyes with distinct optical properties and biocompatibility can be successfully applied to the bio-imaging. In this study, in order to synthesize a highly stable AIE nanoparticles, diketopyrrolopyrrole core based AIE dyes with the triphenylamine derivatives were designed. Since the synthesized AIE dye does not disperse well in an aqueous environment, and may negatively affect cell viability, water-dispersible AIE nanoparticles (NPs) using biocompatible polymer Pluronic F-127 and PMMA were prepared. The prepared AIE NPs showed excellent particle shape and fluorescence intensity by optimizing the content of each biocompatible component. |
| 저자 |
이건호1, 황태규2, 이상윤1, 장성현1, 유의상1, 박종욱3, 최준1
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| 소속 |
1한국생산기술(연), 2한국화학(연), 3경희대 |
| 키워드 |
Aggregation-induced emission; nanoparticles; fluorescence; biocompatibility; bioimaging
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| E-Mail |
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