| 학회 | 한국화학공학회 |
| 학술대회 | 2015년 가을 (10/21 ~ 10/23, 일산 KINTEX) |
| 권호 | 21권 2호, p.1776 |
| 발표분야 | 생물화공 |
| 제목 | Investigation of submerged culture conditions of Cordyceps militaris for enhancement of cordycepin production |
| 초록 | Cordycepin is the main functional component in Cordyceps militaris and it has been received much attention for potential application in bio-industrial field. Recently, Cordyceps is artificially cultivated on solid media for fruiting body development. However, it has several disadvantages on cordycepin production such as long term cultivation time (about 2 ~ 3 month), low productivity and requirement of multi-step extraction and purification, etc. In this study, the conditions of submerged mycelial culture of Cordyceps were investigated for short term production of cordycepin. Two strains (Cordyceps militaris KCTC 6064 and KCTC 6862) were cultured in a liquid minimal medium (pH 5 - 7) and the cultivation profiling was performed at 25 - 37℃ temperature for 5 days. As a result, Cordyceps militaris KCTC 6862 was shown about 2.5-fold enhanced cordycepin production compared with KCTC 6064. |
| 저자 | 김승욱1, 박철환2, 이주훈1, 김동섭1, 최한석1, 이자현1, 이수권1 |
| 소속 | 1고려대, 2광운대 |
| 키워드 | cordycepin; cordyceps militaris; submerged cultivation; growth factors |
| 원문파일 | 초록 보기 |
