| 학회 |
한국화학공학회 |
| 학술대회 |
2020년 가을 (10/14 ~ 10/16, e-컨퍼런스) |
| 권호 |
26권 1호, p.344 |
| 발표분야 |
생물화공 |
| 제목 |
An amperometric biosensor based on Co-hemin Metal-Organic frameworks for lactose detection of dairy product |
| 초록 |
Metal-organic frameworks (MOFs) formed by metal ions and organic linkers through strong coordination bonds. MOF has unique physical and chemical properties including large specific surface area, high porosity, numerous many active sites and post-synthesis modification. MOFs have been extensively applied in several areas, such as catalysis, energy, gas storage and drug delivery. Recently, MOFs have been interested in application of electrochemical biosensors. Because it provides large specific surface area to load enzymes, the performance of enzyme activity and stability could be improved. In this study, a MOF was synthesized by cobalt and hemin to develop an electrode for efficient detection of lactose containing in dairy products. The cellobiose dehydrogenase from Phanerochate chrysosporium (PcCDH) was immobilized on the Co-hemin MOF/chitosan modified electrode to establish a lactose biosensor. The lactose based biosensor showed an excellent performance with broad linear range and good selectivity. This demonstration indicated the feasibility of Co-hemin MOFs/chitosan based biosensor using PcCDH for detection of lactose containing in dairy products. |
| 저자 |
최한석1, 김형렬1, 김은정1, 김경래1, 유하영2, 이자현3, 박철환4, 김승욱1
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| 소속 |
1고려대, 2상명대, 3동양미래대, 4광운대 |
| 키워드 |
생물공정 |
| E-Mail |
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| 원문파일 |
초록 보기 |
