| 학회 | 한국고분자학회 |
| 학술대회 | 2004년 봄 (04/09 ~ 04/10, 고려대학교) |
| 권호 | 29권 1호, p.308 |
| 발표분야 | 기능성 고분자 |
| 제목 | Colloidal Biosensors using the modified Poly(acryl amide/styrene) Nanoparticle |
| 초록 | Abstract Biosensors based on colloids possess much larger surface, which can be utilized for many applications requiring high resolution and sensitivity. In this work the specific interactions between lectins and sugar hybrids, the synthesized GluNAc (N-acetyl-D-glucosamine) and glucose linked to the first position on the carbon of sugar, were investigated. The colloidal biosensor has been synthesized by modified emulsifier-free emulsion copolymerization of acryl amide having ether-linked GluNAc(or glucose) and styrene monomer. The GluNAc and Glucose play a role of immobilized probe, and WGA (wheat germ agglutinin) lectin and Con (Convanavalin) A were used for this study. Molecular recognition was done by surface pressure and electrophoretic mobility analyses, which depends on the degree of hydrophobic interactions between the surfaces of the colloids with sugars. |
| 저자 | 이정열, 정인우, 김중현 |
| 소속 | 연세대 |
| 키워드 | biosensors; colloids; sugar; lectin |
