화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관)
권호 34권 2호
발표분야 의료용 고분자 부문위원회
제목 Preparation of porous poly(3-hydroxybutyrate-co-3-hydroxyvalerate) /hydroxyapatite nanocomposite for tissue engineering
초록 Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV) has been developed and commercialized as ideal candidates for the substitution of non-biodegradable polymeric materials in commodity application because of their biodegradability and easy processability. The biocompatibility of hydroxyapatite(HA) is closely related to its similarities with human hard tissues. Scaffolds consist of PHBV and nano-sized HA were prepared using the salt-leaching and Hot-press machine. PHBV/HA was blended with NaCl by the melting blend method. The blends were compression molded into thin sheet of about 1.5mm thickness using a hot-press machine at molding temperature of 180℃. Then, the scaffolds were immersed into an excess amount of water for dissolving NaCl. In this study, the preparation, degradation behavior, surface morphologies and mechanical properties of porous poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV) foams are described.
저자 백진영, 강인규, 싱즐챠이, 채원표
소속 경북대
키워드 Porous scaffolds; PHBV; Hydroxyapatite
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