화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU))
권호 26권 1호
발표분야 포스터-생물공학
제목 Preparation of glycol chitosan- fucoidan nanocomplex by ionic interaction for antiinflammatory application
초록 To improve the bioavailability efficiency of fucoidan, glycochitosan- fucoidan nanocomplex(GC-FuNaP) has been investigated. We the anti-inflammatory activities of the GC-FuNaP were investigated using Raw 264.7 cells treated with lipopolysaccharide (LPS). Treatment with GC-FuNaP showed 100% or more cell viability at the concentration 200ppm. The protein expression of iNOS, and COX-2 as observed by western blotting, was decreased by GG-FuNaP. In conclusion, GC-FuNaP may affect inflammatory factors as a potential anti-inflammatory agent. These GC-FuNaP would prove useful application in the functional food, cosmetic and pharmaceutical industries.
저자 김진1, 이창문1, 황은주1, 이호준1, 장경철2, 이숙영1, 김춘성1
소속 1조선대, 2(주)코비스
키워드 fucoidan; glycol chitosan; anti-inflammatory; ionic compelx
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