화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2014년 봄 (04/30 ~ 05/02, 제주국제컨벤션센터)
권호 18권 1호
발표분야 포스터-환경.에너지
제목 Stimuli-responsive spiropyran confugated biomaterials
초록 Spiropyrans are demandable photochromic compounds, which can easily be interconverted between ring-closed colorless spiropyran (SP) and colored ring-opened merocyanine (MC) form. We designed thermo and photodual responsive behavior of biocompatible SP-Pluronic micelles after successful conjugation of spiropyran onto Pluronic backbone as fluoresent biomaterial. Also we synthesized spiropyran conjugated hyaluronic acid (HA-SP). The next mixed grapheme oxide (GO). Functionalization was performed by HA-SP, where HA serves as the target molecule and spiropyran constructs the whole composition as fluorescent material. Therefore, our exploitation fluorescent biomaterial can be a novel applicant as a fluorescent probe to identify the cancer cell along with a potential biocompatibility.
저자 정찬진, 이기백, 박성영
소속 한국교통대
키워드 Spiropyran; Photochromic; Pluronic; Hyaluronic acid; Grapheme oxide; biomaterials.
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