| 초록 |
Hydrogel is a three-dimensional (3D) soft and highly hydrophilic polymeric-network that can swell in water and imbibe a high water amount. Hydrogels have been used widely in various biomedical applications. Hydrogel may provide a fluidic tissue-like 3D microenvironment by maintaining the structural network for tissue engineering. However, their low mechanical performance limits their broad applicability. This property causes substantial challenges in designing and preparing strong hydrogel-networks. Therefore, we report the triple-network hybrid hydrogel system with enhanced mechanical properties by incorporating dual-crosslinking and nanofillers (e.g., montmorillonite (MMT), graphene nanosheets (GNS)). In this study, we prepared hybrid hydrogels composed of polyacrylamide, poly (vinyl alcohol), sodium alginate, MMT, and MMT/GNS through dynamic crosslinking. The results exhibited enhanced structural and mechanical properties, good biocompatibility of hybrid hydrogels. |
