| 초록 |
Polymer self-aggregates are being extensively studied to emulate self-assembly in biological systems and also use them in a variety of biological and industrial applications. This study demonstrates a novel strategy to prepare polyaspartamide self-aggregates incorporated with metallic nanoparticles in a pure aqueous solution. We synthesized poly(2-hydroxyethyl aspartamide) (PHEA) substituted with octadecyl chains, which could form micelle-like self-aggregates in the aqueous solution and physically associated with metallic nanoparticles. Then, in situ encapsulation of metallic nanoparticles within the PHEA self-aggregates generated polymer clusters that possess nanoparticles, because of the increase of the hydrophilic mass ratio to total mass of PAHA, f (w). This new strategy to prepare organic-inorganic hybrid cluster system would greatly serve to facilitate the control of self-assembly and ultimately improve the functionality of drug delivery and cosmetic devices. |
