초록 |
Polymer-based materials are increasingly utilized as platforms for investigating and optimizing biological interactions for biomedical applications, such as tissue engineering, drug delivery and biosensors. Most conventional polymers adopted for this purpose serve as mechanical support and lack functional diversity to account for the complexity of biological systems. Herein, multifunctional polymer systems, based on polyaspartamide and hyperbranched hyperbranched polyglycerol, are introduced. Their ability to acquire multifunctionality through simple chemical modifications allowed efficient modulation of physicomechanical and bioactive properties of soft biomaterials. In addition, they could also be integrated with other polymers to develop hybridized materials with advanced functions. The biomedical potential of these polymers was demonstrated as bioinks for 3D bioprinting and injectable and biodegradable drug delivery systems. |