화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터)
권호 38권 2호
발표분야 의료용 고분자 부문위원회
제목 Synergy Effect of Phototherapy by using Nanogel containing both Photodynamic and Photothermal Agent
초록 A chitosan modified, Pluronic-based nanogel that contains gold nanorods (GNRs) and chlorin e6 (Ce6) was constructed as a dual phototherapeutic agent for photodynamic therapy (PDT) and photothermal therapy (PTT). This combined phototherapy system showed no photo-quenching between photosensitizer (Ce6) and GNRs, thus enabling independent PDT and PTT process. Both in vitro and in vivo, the synergy effect between PDT and PTT was dependent on the sequence of PDT and PTT.
저자 김만세, 김자영, 최원일, 태기융
소속 광주과학기술원 신소재공학부
키워드 Pluronic nanogel; gold nanorod; chlorin e6; PTT; PDT
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