| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
OLED 소재 및 소자기술 동향(분자전자 부문위원회) |
| 제목 |
The Patterning of Mesenchymal Stem Cells on Fluorescent Pattern Polymer |
| 초록 |
Photo-reaction of a fluorescent polymer, s-triazine bridged p-phenylene vinylene polymer (STPPV), by UV exposure resulted in fluorescence quenching and a change in surface wettability. The UV-exposed region was not only highly bio-compatible but also provided selective mesenchymal stem cells (MSCs) attachment on it. This selective attachment of MSCs on fluorescent pattern films resulted from hydrophilic interaction between UV exposed region and extracellular matrix (ECM) proteins such as collagen and gelatin. Also, the proliferation rate and differentiation rate of MSCs cultured on UV exposed surface (DTOPV+UV) was higher than that of the unexposed surface. The cell location and pattern images were easily detected through a microscope with or without an excitation probe beam by using the emission from the DTOPV pattern. These studies provide a potential opportunity for the investigation of stem cells including bioengineering and tissue regeneration. |
| 저자 |
유정목, 허준석, 이지예, 김한수, 김현옥, 김은경
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| 소속 |
연세대 |
| 키워드 |
Fluorescent polymer; Mesenchymal stem cell; pattern; photo-oxidation
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| E-Mail |
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