화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터)
권호 35권 1호
발표분야 대학원생 구두발표
제목 Composite Microwell Arrays via Controlled Photo-polymerization in Microfluidic Device
초록 Hydrogel-based microfluidic platform has been extensively investigated because it is easy to position at microfluidic system by photo-polymerization and can perform both sensing and actuation functions. Here we propose novel method for preparation of composite microwell arrays with response to external stimulation via in-situ polymerization in microfluidic device. Microwell array with two different polymers was fabricated using two step sequential photo-polymerization; polymer with no responsive characteristics as a supporting layer and pH-responsive hydrogel as an actuation layer. Without using photo mask which needs complicated mask aligning process, silicon microdot array was used to define the structure of two polymer layers. Composite microwell array was actuated with pH buffer solution to give complete entrapment of analytes in each well. Hydrogel microwell demonstrated in this study is expected to be utilized in multiplex biomolecular analysis.
저자 허철준1, 김신현1, 장세규2, 최재훈3, 양승만1
소속 1한국과학기술원 / 광자유체집적소자연구단, 2Univ. of California, 3Santa Babara
키워드 Hydrogel; Microfluidic device; Photo-polymerization
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