| 학회 |
한국고분자학회 |
| 학술대회 |
2012년 봄 (04/12 ~ 04/13, 대전컨벤션센터) |
| 권호 |
37권 1호 |
| 발표분야 |
대학원생 구두발표 |
| 제목 |
Reversible Origami Folding of Hydrogel Bilayer Microparticles for Robust Microcarriers |
| 초록 |
Microcapsules for transport and controlled release have long been studied because of the high demand for practical delivery systems in the pharmaceutics and cosmetics fields. Multiphase emulsion drops have provided efficient templates for microcapsules, and various feasible methods have been developed for controlled release. However, the emulsion-based approach has limitations for the in situ control of membrane permeability. In this study, we report a facile method for creating bilayer microparticles which exhibit structural transformation to microcapsules by anisotropic volume expansion. Planar hydrogel microparticles, consisting of active layer and passive layer, can readily transform to 3D microcapsule by 2D bending of the bilayer when active layer swells at specific environment. Therefore, hydrogel bilayer structures enable in-situ encapsulation of micro- to nano-scopic active ingredients by a reversible transformation to microcapsules with a closed compartment. |
| 저자 |
심태섭1, 김신현2, 허철준1, 전환철1, 양승만1
|
| 소속 |
1카이스트, 2Harvard |
| 키워드 |
Hydrogel; Microencapsulation; Origami folding
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| E-Mail |
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