| 학회 |
한국재료학회 |
| 학술대회 |
2011년 가을 (10/27 ~ 10/29, 신라대학교) |
| 권호 |
17권 2호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Novel biodegradable chitosan-tyramine-gelatine hydrogel/bioactive glass ceramic composite for bone tissue engineering |
| 초록 |
Hydrogels consisted of the tyramine-conjugated gelatin and chitosan derivative were obtained by enzymatic crossliking under physiological conditions using horseradish peroxidase (HRP) as a catalyst and hydrogen peroxide (H2O2) as an oxidant. The hydrogel structure was highly porous and showed unique channelized morphology with an extensive branching of the channels. Composite of chitosan–tyramine-gelatin hydrogel with bioglass were prepared by blending of chitosan and gelatin with sol-gel derived CaO-P2O5-SiO2 bioactive glass gel. The prepared composite was characterized using FTIR, SEM and XRD. The effect of bioactive glass in the polymer-ceramic matrix was evaluated in terms of biocompatibility by using MTT assay and confocal microscopy based cell proliferation analysis. |
| 저자 |
Dibakar Mondal1, Nguyen Thuy Ba Linh2, Byong-Taek Lee3
|
| 소속 |
1Department of Biomedical Engineering & Materials, 2School of Medicine, 3Soonchunhyang Univ. |
| 키워드 |
hydrogel; gelatin; tyramine; bioactive glass; composite
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| E-Mail |
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