| 학회 |
한국재료학회 |
| 학술대회 |
2021년 가을 (11/24 ~ 11/26, 경주 라한호텔) |
| 권호 |
27권 2호 |
| 발표분야 |
G. 나노/박막 재료 분과 |
| 제목 |
In-Vitro Evaluation of PCL-Gelatin Based Artificial Membrane Bones |
| 초록 |
In this study, we developed a novel artificial bone membrane for bone regeneration. Polycaprolactone (PCL), gelatin (GEL) and tri-calcium phosphate (TCP) membrane were fabricated using electrospinning process. Microstructures and morphologies of GEL loaded PCL (PCL/GEL), GEL and TCP loaded PCL (PCL/GEL/TCP) were carried out using a scanning electron microscope equipped with an energy dispersive X-ray spectroscope. In-vitro studies using MC3TC-E1 pre-osteoblast cells showed that PCL/GEL/TCP membranes were excellent biocompatibilities and supported the cell attachment and proliferation. To make the artificial membrane bone, we seeded bone-marrow-derived mesenchymal stem cells (rBMSCs) on the PCL/GEL/TCP membrane to differentiated into osteoblasts. The differentiated cells were evaluated with alizarin red staining and western blots by 7 and 14 days. |
| 저자 |
Hyejin Tae1, Byong-Taek Lee2
|
| 소속 |
1Department of Regenerative Medicine, 2College of Medicine |
| 키워드 |
<P>Artificial Bone; Membrane </P>
|
| E-Mail |
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