| 학회 |
한국공업화학회 |
| 학술대회 |
2018년 가을 (10/31 ~ 11/02, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
22권 2호 |
| 발표분야 |
정밀화학_포스터 |
| 제목 |
Antioxidative activities of caffeoyl-tripeptides |
| 초록 |
Antioxidants play a critical role in treating degenerative diseases and delaying aging of dermal tissue. A representative example is caffeic acid (CA) which is one of the antioxidants found in plants. However, CA itself is not suitable for long-term storage due to its poor stability under an ambient condition. We previously reported that caffeoyl-Pro-His dipeptide (CA-Pro-His-NH2) showed the highest antioxidative activity among the histidine-containing CA dipeptides as well as a higher free-radical scavenging activity and lipid-peroxidation-inhibition activity than those of CA. We assumed that the addition of an amino acid to the C terminal of the CA-Pro-His-NH2 may synergistically enhance its antioxidative activity and long-term storage. Therefore, we synthesized twenty different caffeoyl-prolyl-histidine-Xaa tripeptides and evaluated their antioxidation activities and storages. We hope that the CA-Pro-His-Xaa-NH2 will be used as dermal therapeutic agents. |
| 저자 |
정혜리, 신동식
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| 소속 |
숙명여자대 |
| 키워드 |
Antioxidant; Caffeoyl-prolyl-histidyl-Xaa tripeptides
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| E-Mail |
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