| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 |
23권 2호 |
| 발표분야 |
포스터_정밀화학 |
| 제목 |
Synthesis of caffeoyl-prolyl-histidyl-Xaa tripeptides and evaluation of their antioxidative activities and long-term storage |
| 초록 |
We have reported that caffeoyl-prolyl-histidine-Xaa-NH2 tripeptides (CA-Pro-His-Xaa-NH2) showed strong antioxidative activity among the histidine-containing CA dipeptides as well as a higher free-radical scavenging activity and lipid-peroxidation-inhibition activity than those of CA. It is assumed that the addition of an amino acid to the C terminal of the CA-Pro-His may enhance its antioxidative activity. In this study, long-term storage of CA-Pro-His- Xaa-NH2 was additionally evaluated under certain conditions. Change of NMR and HPLC profiles exhibited the stability with various conditions. We envision that the CA-Pro-His-Xaa-NH2 will be used as cosmetics and dermal therapeutic agents. |
| 저자 |
전영은, 신동식
|
| 소속 |
숙명여자대 |
| 키워드 |
Peptides derivatives; antioxidant; caffeoyl-prolyl-histidine tripeptides
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| E-Mail |
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