화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션)
권호 20권 1호
발표분야 콜로이드계면화학_포스터
제목 Myotube-based bio-actuator working by self-folding assembly
초록 Significant progress in developing cell-based biohybrid actuators has increasingly been studied. In this study, the integrated myotube-based bio-actuator was fabricated by DLP 3D printer and subsequently filling the cell-matrix composed of Collagen, Matrigel and Myoblasts. In parallel, we prepared a hydrogel actuator consisting of two different layers with significantly different stiffness and capacities to uptake water in response of the environments. Next, electrical stimulation triggered contraction of cells in the muscle band and movement of the integrated cell-based actuator. This cell-based bioactuator system could be further developed as a integrated cellular machines and systems to provide drug screening, programmable tissue engineering, biomimetic machine design and micro-scale actuators and microfluidic flow control. We believe that the integrated bioactive system developed in this study will be highly useful for a broad array of Organ-on-a-chip such as valves.
저자 조성우, 김희진, 신성규, 이기흥, 오승주, 정재현
소속 숭실대
키워드 Myotube; Actuator; Hydrogel; Lab on a Chip
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