화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2012년 봄 (04/25 ~ 04/27, 제주 ICC)
권호 18권 1호, p.478
발표분야 생물화공
제목 Real-time and label-free detection of liver cancer using aptamer immobilized nanosensor
초록 Nanoscale biosensors are emerging as one of the most impressive platforms for specific identification of biomolecules in the life sciences, with the nanotechnology revolution up to the scale that concert with the biological system. To date, there have been many reports for the nanoscale biosensors based on antigen-antibody interactions. In this work, we demonstrated novel aptamer immobilized nanosensor which is one of the promising platforms in biosensor applications for cancer diagnostics. It is expected that aptamer-antigen interactions can give us more effective options than antibody based biosensors due to their smaller size as compared to that of antibody generally. To evaluate and prove these effects in this work, the aptamer functionalized ZnO/a-C core-shell nanowire based nanosensors were successfully demonstrated for the real-time and label-free detection of Hepatocellular Carcinoma (HCC) markers
저자 김진태, 임연호, Deepti Sharma, Rizwan, 구아영, 송정근, 서지혜, 육영근
소속 전북대
키워드 AFP aptamer
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