| 초록 |
Poly (2-hydroxyethyl methacrylate) (poly (HEMA)) based hydrogel has been researched for application in various fields of bio-industry due to their hydrophilic and relatively high mechanical properties. However, there are some problems of relatively poor water content, poor cell attachment and complex fabrication technique for application. In this work, poly ((2-hydroxyethyl methacrylate)-(2-(Methacryloyloxy) ethyl trimethylammonium chloride solution)) (poly (HEMA-MAETC)) hydrogel beads were successfully fabricated via electro-spraying method by photo-polymerization which is easy to control process. By addition of MAETC as a cationic monomer, swelling behavior was enhanced with maximum 2500 (%) equilibrium water content which is 20 (%) higher value compared to poly(HEMA-EGDMA) and elastic modulus also was 3 times-enhanced from 130 to 630 (kPa). Additionally, cell affinity was also enhanced by interaction between positive charged poly (HEMA-MAETC) bead and negative charged cell. |
