화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU))
권호 26권 1호
발표분야 포스터-생체재료
제목 Alginate coated chitosan microparticles for cancer therapy
초록 One of the most important factors in the drug delivery system is the binding bewteen receptors penetrating through the cell wall of target cells and ligands and subsequent endocytosis of the drug. In order for this mechanism works, the drug carriers should consist of materials and structures favorable for the interaction with target cells. The layer-by-layer method for the preparation of drug carriers is a essential strategy to allow structural stability, endocytosis, and controlled drug release. In this study, microparticles impregnated with anticancer drugs were prepared using the layer by layer method, and their functional and physical properties were analyzed using various analytical instruments including scanning electron microscope and Fourier transform infrared spectroscope. The drug was released from the microparticles in a controlled manner.
저자 김현지, 도해빈, 쟝위취엔, 이우걸
소속 단국대
키워드 Chitosan; drug delivery system; layer-by-layer method; controlled drug release
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