학회 | 한국공업화학회 |
학술대회 | 2017년 봄 (05/10 ~ 05/12, 광주 김대중컨벤센센터(Kimdaejung Convention Center)) |
권호 | 21권 1호 |
발표분야 | 생물공학 |
제목 | Identification of novel thermostable ω-transaminase and its application for enzymatic synthesis of chiral amines at high temperature |
초록 | A novel thermostable ω-transaminase from Thermomicrobium roseum which showed broad substrate specificity and high enantioselectivity was identified, expressed and biochemically characterized. The advantage of this enzyme to remove volatile inhibitory by-products was demonstrated by performing asymmetric synthesis and kinetic resolution at high temperature Asymmetric synthesis of aromatic β-amino acids using ω-transaminase. |
저자 | 성시형1, 전현우1, 윤상한1, Kanagavel Deepankumar2, 윤형돈1 |
소속 | 1건국대, 2영남대 |
키워드 | enzymatic synthesis; transaminase |