| 초록 |
In this study, an extraction technique of biomass-derived paclitaxel using ultrasonic cavitation bubbles and gas bubbles is presented. Extraction efficiency has been dramatically improved, and the time required for extraction has been reduced compared to conventional methods. In particular, the synergistic effect of mixing cavitation bubbles and gas bubbles during extraction was confirmed. As the ultrasonic power and gas flow rate increased, the synergistic effect increased. As a result of investigating the mechanism of extraction in which cavitation and gas bubbles were introduced, it was found that the bubble itself severely damage the biomass surface, thereby enabling easy extraction. In addition, the extraction behavior was quantitatively investigated by calculating the effective diffusion coefficient and mass transfer coefficient of paclitaxel. [This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Government of Korea (MSIT) (Grant Number: 2021R1A2C1003186).] |
