| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
[정밀화학] 정밀화학 기술 - COVID-19 시대 |
| 제목 |
Development of New Methodologies for practical synthesis of Pharmaceuticals |
| 초록 |
The development of methodologies has been studied for synthesis of pharmaceuticals. In particular, carbonyl addition is one of the fundamental reactions forming C–C bonds to construct structurally complex organic molecules from small molecules. For the carbonyl addition, transition metal catalyzed redox-triggered C–C bond forming reactions of alcohols have been developed via transfer hydrogenation. Combined redox events are more efficient in terms of step and atom-economy by delivering nucleophile-electrophile pairs in situ from π-unsaturates and alcohols. Furthermore, flow chemistry has been also one of the powerful ways to develop efficient methodologies. Recent reports have detailed the attractive features of transferring a photochemical reaction to flow process due to high photon concentration. Herein, this seminar introduces several works regarding transition metal catalyzed redox triggered C–C couplings in batch and photochemistry in continuous flow process. |
| 저자 |
박보영 |
| 소속 |
경희대 |
| 키워드 |
Transition-metal catalysis; photochemistry; flow chemistry
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| E-Mail |
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