| 학회 |
한국공업화학회 |
| 학술대회 |
2016년 봄 (05/02 ~ 05/04, 여수 엑스포 컨벤션) |
| 권호 |
20권 1호 |
| 발표분야 |
환경에너지_포스터 |
| 제목 |
Quinine Intercalated Natural Hectorite Clay Layered Hybrid Nanocomposite for Controlled Drug Delivery Application |
| 초록 |
The present study report the controlled drug releasing ability of natural smectite hectorite clay materials (NHT) using quinine drug. Quinine (Qu) is an antimalarial drug loaded on the natural hectorite clay mineral via cation exchange mechanism to form quinine intercalated natural hectorite nanocomposite (QNHT). All the materials were characterized by XRD, FT-IR, BET Surface area and thermogravimetric TGA/DTA analysis to study the textural and thermal stability of the pure and modified hectorite materials. Subsequently the QNHT used to carry in-vitro drug delivery release behavior of intercalated quinine drug on buffer environment with respective intestinal fluid and gastric fluid at pH =1.2 and 7.4 and also compared with pure quinine drug. On the basis of present studies it can be conclude that the QNHT nanocomposite have the potential for developing in to a controlled release formulation for oral drug delivery of an anti-malarial drug quinine. |
| 저자 |
Pawar radheshyam rama, 이승목
|
| 소속 |
가톨릭관동대 |
| 키워드 |
Natural hectorite; Quinine; Anti-malarial drug; Controlled drug delivery
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| E-Mail |
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