화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2006년 봄 (04/06 ~ 04/07, 일산킨텍스)
권호 31권 1호
발표분야 고분자 합성
제목 Preparation of Surface-Anionized Poly(vinyl alcohol/methacrylic acid) Copolymer Hydrogel Bead
초록 For the purpose of obtaining surface-anionized poly(vinyl alcohol(PVA)) hydrogel beads, vinyl acetate (VAc) and methacrylic acid (MAA) were copolymerized by the suspension polymerization and followed by the saponification. It was confirmed by 1H-NMR that the copolymerized beads contained carboxylic acid groups in their surface. Poly(VAc-co-MAA) beads were completely saponified in the heterogeneous system. The saponification reaction was faster than that of PVAc microspheres. We observed the swelling property of saponified PVA beads treated in the acidic solution and in the alkaline solution successively. Saponified beads shrank in acidic solution and swelled in alkaline solution reversibly. Dichlofenac was loaded in the saponified beads and its release behavior was investigated according to pH.
저자 조수혁, 이세근, 류원석
소속 영남대
키워드 surface-anionized; hydrogel bead; release behavior
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