초록 |
Microfluidic devices including microarray is one of various advantages for chemical and biological analysis provided from droplet-based microfluidic system. We report a selective concentrate generation microfluidic device to generate arrays of moving droplets containing variation of chemical concentration between individual drops.In addition, we present a programmable droplet-based microfluidic device including array chamber pressed negatively. In this system, we describe a non-stop passive strategy to create precise and quantitative gradation in array chamber. Herein, we count the maximum number of droplets within array chamber. As a result, we confirm the accurate ratio of the material to comprise the droplets in the array chamber. Finally, controlled the ratio in continuous array chambers demonstrate selective concentration. Thus, our method could be valuable as a useful platform to study fundamental biological and chemical reactions, high-throughput and high-resolution screening, or combinatorial synthesis or analysis. |