| 학회 |
한국재료학회 |
| 학술대회 |
2010년 봄 (05/13 ~ 05/14, 삼척 팰리스 호텔) |
| 권호 |
16권 1호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Electrospun PVA/Gelatin nanofibers for drug delivery and their cellular compatibility |
| 초록 |
In this study, PVA/Gelatin nanofibers were fabricated via electrospinning method. Morphology of nanofibers was investigated in different ratios of PVA/Gelatin. Mechanical properties of membrane nanofibers from various ratios of PVA and Gelatin were also studied. In addition, potiential apply of Raspherry ketone incorroporation in nanofibers for tissue engineering was examined by drug release, integrity in water and cellular compatibility. Results demonstrated that mechanical properties of membranes increase when increase of content of PVA component. Raspherry ketone released characteristic can be controlled by pH value, crosslinking time and ratio PVA/Gelatin. In vitro study show that nanofibers membranes structure promoted the attachment of fibrolast cell, maintain characteristic cell morphology and viability through the period of study.
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| 저자 |
Trinh Quang Bao1, Yang-Hee Kim2, Young-Ki Min3, Ho-Yeon Song1, Byong-Taek Lee2
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| 소속 |
1Department of Biomedical Eng. & Mater., 2School of Medicine, 3Soonchunhyang Univ. |
| 키워드 |
Electrospinning; drug delivery; PVA; Gelatin
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| E-Mail |
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