| 초록 |
Despite the recent progress in bone therapy using titanium-based implants, compromised healing due to the inadequacy of metal implants for long term usage is still a major issue. Studies into bone repair mechanisms have revealed that cells are driven by electrical signals, and that subsequently, increasing piezoelectric properties of hydroxyapatite (HAp) increases the speed of osseointegration. Herein, we propose a novel implant coating material, where surface-modified HAp fillers are incorporated in P(VDF-TrFE). The ferroelectric matrix functions to enhance the dielectric property of HAp in such a way that the composite promotes electrochemical stimulus on the bone, without any external bias. Taken together with the advantages of its simple fabrication methods and outstanding flexibility, results of this study confirm the promising potential of our HAp-based membrane as viable material to assist endogenous bone growth. |
