| 학회 | 한국재료학회 |
| 학술대회 | 2014년 봄 (05/15 ~ 05/16, 창원컨벤션센터) |
| 권호 | 20권 1호 |
| 발표분야 | D. 바이오 재료(Biomaterials) |
| 제목 | Mechanical Strength and in Vitro Performance of β-Tricalcium Phosphate Scaffolds by a Polyurethane Foam Replication Technique |
| 초록 | This study aimed to explore the characterization and mechanical strength of beta-tricalcium phosphate (β-TCP) scaffold. At first, β-TCP scaffold was fabricated by replica method using polyurethane (PU) foam as a passing material; follow by mixing slurry of poly vinyl butyl (PVB), commercial β-TCP powder and triethyl phosphate (TEP) stirred vigorously in ethanol (100%). The samples was investigated by optical microscope, FE-SEM, XRD, Instron machine and MTT assay were used to analyze the element, characterize, mechanical strength and cytotoxicity of the β-TCP scaffold. Through the image of optical microscope in low-high magnification presented that the interconnected pore increased as coating time increased whilst the pore size decreased. An image of FE-SEM showed the surface roughness with an interconnected pore and pore size of approximately 60-100 μm and 150-950 μm respectively, had a compressive strength of 0.88 MPa by using Instron machine. The MTT assays of in vitro cell cultures showed a good ability of the scaffolds to support the proliferation of MC3T3-E1 osteoblast cells at two culture intervals. This research was supported by National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (No. 2011-0028709 and 2013R1A1A2012322) and Regional Strategic Industry project in 2013 (No. R0002274). |
| 저자 | Phonelavanh Manivong1, T.S.N. Sankara Narayanan2, Yu Kyoung Kim3, Il Song Park4, Tae Sung Bae5, Min Ho Lee1 |
| 소속 | 1Department of Dental Biomaterials and Institute of Biodegradable material, 2Institute of Oral Bioscience, 3BK21 Plus Program, 4School of Dentistry, 5Chonbuk National Univ. |
| 키워드 | beta-tricalcium phosphate (β-TCP) scaffold; pore size; MTT assay |
