| 학회 | 한국재료학회 |
| 학술대회 | 2012년 봄 (05/17 ~ 05/18, 무주덕유산리조트) |
| 권호 | 18권 1호 |
| 발표분야 | D. 바이오재료(Biomaterials) |
| 제목 | Apatite-forming ability of sol-gel derived titania containing silicon or aluminumadditives in a simulated body fluid |
| 초록 | Chemical modification on surface of titanium alloys provides osteoconduction since the chemical modification produces a titana layer that has capability to form bone-like hydroxyapatite (HAp, Ca10(PO4)6(OH)2) after exposure to body fluid. The potential of HAp formation, on titania can be provided by induction of heterogeneous nucleation of HAp after exposure to the fluid. However, the detailed prerequisite conditions for the HAp nucleation on the titania have not been clarified yet. In the present study, we report capability of HAp formation on modified titania gels by doping silicon or aluminum in the range up to 10 mol% as nominal compositions. The difference in surface characteristics of the modified titania was examined to evaluate their potential of the HAp formation in simulated body fluid (SBF). Sol-gel processing was applied to prepare titania modified with doped silicon or aluminum, in its nominal composition ranging from 0 to 10 mol%. The prepared gels with doped silicon or aluminum were abbreviated as TSx or TAx, respectively, where x means nominal composition of the doped metal (mol%). Zeta potential of TAx showed a definite change from negative to positive charge with addition of 3 mol% of aluminum and more, while that of TSx showed negative charges with slight shift to be less with increasing silicon contents. After the soaking of the samples in SBF for 14 d, scanning electron microscopic observation of the pure titania free from the silicon and aluminum indicated the formation of precipitate. In contrast, when the TSx and TAx contain silicon or aluminum at concentration of more than 1 mol%, all the samples did not form HAp after soaking in SBF for 14 d. The increased phosphrous adsorption with increasing metal contents might reduce the degree of supersaturation with respect to HAp in SBF. Acknowledgements This work was supported by Grant-in-Aid for Scientific Research (No. 22107007) on the Innovative Areas: “Fusion Materials” (Area no. 2206) from the Ministry of Education, Culture, Sports, Science and Technology (MEXT). |
| 저자 | Euisup SHIN1, Ill Yong KIM2, Sung Baek CHO1, Chikara OHTSUKI2 |
| 소속 | 1Graduate School of Engineering, 2Nagoya Univ. |
| 키워드 | Titanium oxide; Surface charge; Hydroxyapatite; Sol-gel processing |
