학회 |
한국재료학회 |
학술대회 |
2010년 가을 (11/11 ~ 11/12, 무주리조트) |
권호 |
16권 2호 |
발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
제목 |
Characterization of Aqueous Pluronic® F127 based on Gamma-ray doses |
초록 |
Gamma-ray irradiation is a very useful tool to improve the physicochemical properties of various biodegradable polymers without a heating and cross-linking agent. Pluronics are polyoxyethylene-plyoxypropylene-polyoxyethylene (PEO-PPO-PEO) triblock copolymers. When the pluronic® F127 (F127) concentrations are at or above 16% in the aqueous solutions, they show interesting thermal behaviors. The F127 forms soft gels when they rise to body temperature, which are suitable for applications as a bone substitute. The aim of this work was to observe the thermal behaviors of the F127 solutions in gelation phenomena. The F127 solutions were dissolved in deionized water homogeneously at low temperature (about 4°C). The solutions were irradiated by using 60Co gamma-ray at a dose rate of 10 kGy/hr. The total irradiation dose was ranged from 25 kGy to 500 kGy. The F127 solutions were characterized by varying the concentration and analyzing their thermal behaviors. |
저자 |
Sun-Young Jo1, Youn-Mook Lim2, Hui-Jeong Gwon3, Jong-Seok Park4, Heungsoo Shin5, Young-Chang Nho1
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소속 |
1Radiation Research Division for Industry & Environment, 2Advanced Radiation Technology Institute, 3Department of Bioengineering, 4Division of applied Chemical and Bio Engineering, 5Hanyang Univ. |
키워드 |
Pluronic F127; Gamma-ray; Hydrogel
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E-Mail |
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