| 학회 |
한국고분자학회 |
| 학술대회 |
2009년 가을 (10/08 ~ 10/09, 광주과학기술원 오룡관) |
| 권호 |
34권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Injectable Biodegradable Hydrogels for Drug Delivery and Tissue Engineering |
| 초록 |
We have developed an injectable biodegradable hydrogel system using enzyme-mediated reaction for drug delivery and tissue engineering applications. This system does not involve toxic chemicals or reactions in the hydrogel formation process, thus allowing therapeutic proteins, growth factors and cells to be incorporated without damaging these biological molecules. This system also allows us to control the mechanical strength of the hydrogel, while achieving a rapid gelation rate. This feature offers several advantages for controlling the degradation, drug release and cell proliferation or differentiation, while preventing uncontrolled leakage of the bioactive agents during the gelation process in vivo. |
| 저자 |
Motoichi Kurisawa1, Fan Lee2, Li Shan Wang3, Joo Eun Chung4
|
| 소속 |
1Institute of Bioengineering and Nanotechnology, 231 Biopolis Way, 3The Nanos, 4#04-01 Singapore 138669 |
| 키워드 |
a |
| E-Mail |
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