| 학회 |
한국화학공학회 |
| 학술대회 |
2004년 가을 (10/29 ~ 10/30, 호서대학교(아산캠퍼스)) |
| 권호 |
10권 2호, p.2285 |
| 발표분야 |
촉매/반응공학 |
| 제목 |
Development of Coumarin Modified Si-MCM-41 for Drug Delivery System |
| 초록 |
The mesoporous Si-MCM-41 molecular sieves using different surfactant for different pore sizes have been synthesized under hydrothermal conditions. The materials were modified by coumarin derivatives for the properties of hinged double doors (either pore size closed). The surfactants were removed from the synthesized Si-MCM-41 using dilute hydrochloric acid under extraction method. The materials have been used for absorption and released of drug as ibuprofen under photo-irradiation. The ibuprofen absorbed by the mesoporous materials when the coumarin dimersed within pores while the ibuprofen released slowly from the materials when the dimersed coumarin was cleavaged under photo-irradiation conditions. The materials results and absorbed-released results will be presented. |
| 저자 |
이태규1, Manickam Selvaraj1, 김병후2, 민병렬1
|
| 소속 |
1연세대, 2Yonsei Center for Clean Technology |
| 키워드 |
Mesoporous MCM-41 material; Coumarin modified Si-MCM-41; Host-guest interactions; Drug absorbents; Drug release
|
| E-Mail |
|
| 원문파일 |
초록 보기 |
