| 학회 |
한국화학공학회 |
| 학술대회 |
2017년 봄 (04/26 ~ 04/28, ICC 제주) |
| 권호 |
23권 1호, p.1375 |
| 발표분야 |
신진연구자 심포지엄 |
| 제목 |
High Throughput Synthesis of Nanoparticles Using a Coaxial Turbulent Jet Mixer |
| 초록 |
Nanoparticles have shown great promise for the diagnosis and therapy of major diseases such as cancer, cardiovascular, and infectious diseases. Use of microfluidics for synthesis of these nanoparticles has been of great interest due to controllability and reproducibility in their physicochemical properties. However, productivity of microfluidic systems is lower than that of batch reactors due to low flowrates, making it challenging to produce large quantities of nanoparticles required for in vivo or clinical studies. In this work, we developed a novel coaxial turbulent jet mixer capable of synthesizing various types of functional nanoparticles with extremely high production rates suitable for series of in vivo studies and clinical trials, while maintaining the controllability and reproducibility of conventional microfluidic systems. |
| 저자 |
임종민1, Archana Swami2, Laura M. Gilson3, Sunandini Chopra4, Robert Langer4, Omid C. Farokhzad4, Rohit Karnik2
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| 소속 |
1순천향대, 2Brigham and Women's Hospital, 3Harvard Medical School, 4Massachusetts Institute of Technology |
| 키워드 |
Nanoparticles; Turbulent Jet; Nanomedicine
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| E-Mail |
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| 원문파일 |
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