| 학회 |
한국공업화학회 |
| 학술대회 |
2019년 봄 (05/01 ~ 05/03, 부산 벡스코(BEXCO)) |
| 권호 |
23권 1호 |
| 발표분야 |
생체재료_포스터 |
| 제목 |
Adsorption and drug release characteristics of atenolol on mungbean starch based functional molecularly imprinted films |
| 초록 |
Molecular imprinting technology has the advantages of molecular recognition, simple operation, template recycling, and the ability of selective separation of target molecule. In this study, adsorption and release characteristics of mungbean starch based drug delivery films imprinted with atenolol (ATN) were investigated in terms of the plasticizer, temperature and pH and the results were also interpreted by the related mathematical models. The adsorption characteristics of target molecule on ATN-imprinted biomaterial films were better explained by the Freundlich and Sips equation than the Langmuir equation. The binding site energy distribution function was also useful for understanding the adsorption relationships between target molecule and biomaterial films. The drug release of ATN-imprinted biomaterial films followed the Fickian diffusion mechanism, whereas the drug release using artificial skin followed the non-Fickian diffusion behavior. |
| 저자 |
김한성1, 황민진1, 이창문1, 심왕근2, 윤순도1
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| 소속 |
1전남대, 2순천대 |
| 키워드 |
adsorption; modelling; molecularly imprinted films; drug release; atenolol
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| E-Mail |
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