| 학회 |
한국재료학회 |
| 학술대회 |
2016년 가을 (11/16 ~ 11/18, 경주 현대호텔) |
| 권호 |
22권 2호 |
| 발표분야 |
B. 나노화학/바이오 재료 분과 |
| 제목 |
Development of microfluidic devices for stem cell research |
| 초록 |
We developed the microfluidic device for studying stem cell-derived differentiation. The microfluidic device was filled with the biocompatible hydrogels to culture stem cells in a well-defined microenvironment. The microfluidic device consisted of various micropillar arrays to generate uniform-sized stem cells in a homogeneous manner. The stem cells were docked inside various micropillars to generate stem cell-derived neuronal networks. The stem cells were subsequently cultured within micropillars of the microfluidic device to induce stem cell-derived neuronal differentiation. We demonstrated that a number of neurites were closed connected across micropillars in a systematical manner. Therefore, this micropillar-based microfluidic device could be a useful for regulating the stem cell-derived neurite outgrowth in a controlled manner. |
| 저자 |
김다은, 이종민, 문주윤, 정봉근
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| 소속 |
서강대 |
| 키워드 |
gelatin methacrylate; motor neuron; neural stem cells; microfluidic;
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| E-Mail |
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